Meet Our Palo Alto Advanced Dentists

Our Palo Alto Dentists are dedicated to providing you with the highest quality care. This attitude has made Palo Alto Advanced Dentists a well-respected dental care destination for Palo Alto and the greater Bay Area. In our modern offices, equipped with the latest technologies, our dentists can help improve your self-image, confidence, and well being by perfecting one of your most valuable assets — your smile.

Dr. James Ho, D.M.D., M.P.H.

Dr. James Ho earned his Doctor of Dental Medicine (D.M.D.) and Master of Public Health (M.P.H.) from Harvard University. He attended University of California, Santa Cruz for his undergraduate degree in Biochemistry and Molecular Biology, with a minor in Computer and Information Sciences.

A member of the American Dental Association (A.D.A.) and California Dental Association (C.D.A.) and American Association for Functional Orthodontics (A.A.F.O.), Dr. Ho devotes 100% of his time in patient care using the most up-to-date, safe and proven treatment modality that Dr. Ho is uniquely qualified to share with his patients.

In a typical clinical setting, Dr. Ho explains in detail all possible alternate treatment procedures, and obtains consensus on the best treatment plan based on the patient’s need and resources. Many patients complement on Dr. Ho’s repertoire of dental skills that offer them “one-stop” dental care for all their oral health needs.

Dr. James Ho may not be your ultra specialist who promises a better face after he dissembles your entire skull and put it back together from pieces, but with a well-rounded, medical-dental education from Harvard, he immerses himself with such proven high-tech innovations as digital X-ray, hard- and soft-tissue laser, and CAD-CAM (CEREC) dentistry.

He gains rapport and trust from his patients by successfully reviving what several specialists and general dentists deem “hopeless” situations. To be sure, there is no magic wand that Dr. Ho can wave to make those “miracles” possible. Instead, he is able to employ all his skills and disciplines to evaluate and solve problems for each challenging situation. The result is that every patient of his benefits from the amalgamation of technology and 20 years of full-time clinical experience.

Dr. Ho is especially fond of the fields of Functional Jaw Orthopedics and Orthodontics. He provides bone regeneration therapy in addition to scaling and root planing to rejuvenate dental and periodontal health, and he is able to provide root canal treatment, post and core, and crown restoration in one single appointment!

Dr. Ho uses cutting edge techniques to perfect your smiles. One of his specialties is Dental Implant. To learn more about Dental Implant, please visit

Dr. Ho’s bedside manner has an impeccable record: he is a winner of Best Service Award in the Dentist Category for two consecutive years. Dr. Ho is fluent in English, Mandarin and Cantonese.

Dr. Sara Hamed-Negahdar

Dr. Sara Hamed-Negahdar completed her Doctor of Dental Surgery Program at University of Southern California (USC) in 2014 and has been treating patients since. She completed her dual undergraduate degrees in Biology and Sociology at California State University, Northridge with honors (Cum Luda).

Dr. Hamed is a member of the American Dental Association (ADA), California Dental Association (CDA) and Santa Clara County Dental Society (SCCDS) where she is a member of board of directors and serves on different committees, such as Community Service, Continuing Education and Editorial board. She has a long track record of giving back to the community through numerous mission trips to Ensenada, Mexico and Nairobi, Kenya as well as here in the states. She has a passion for bringing healthy smiles to patients faces and enjoys what she does everyday. She is known as the "gentle dentist" with great chairside manner and communication skills.

Competent in performing all aspects of general dentistry using cutting edge technology and materials, Dr. Hamed constantly keeps up to date with new techniques and ways to provide comprehensive diagnosis and treatment planning for adults and children. Patients often express how comfortable Dr. Hamed makes them feel for any dental procedure, by first explaining the procedure in detail, answering any questions they might have and listening to their immediate dental concerns.

During her free time, Dr. Hamed enjoys cooking while listening to jazz music, audio books/podcasts, watching stand-up comedies and skiing during winter.

Dr. Pedro Avendaño, D.D.S.

Dr. Pedro Avendaño graduated with honors from the University of Chile. There he also served as a clinical instructor in fixed prosthodontics, crowns, bridges, as well as implants training for the International Team for Implantology Straumann (ITI).  Prior to coming to California, he served as the director of a group of clinical practices in Santiago, Chile where he focused on Implants and Oral Rehabilitation. He is an active member of numerous dental societies in which he participates in lectures and continued education focused on Endodontics, Oral Surgery, and Implants.  He assisted in a course on Implant Maxi at the Loma Linda University,  School of Dentistry.  He is a member of the California Dental Association, American Dental Association, and American Academy of Implant Dentistry since 2011. Dr. Avendaño enjoys mountain skiing and spending time with his family.

Dr. Eddy Wang

Dr. Eddy Wang graduated from the University of Pittsburgh, school of dental medicine in 2011 with the degree of DMD. He then completed the General Practice Residency at St. Elizabeth trauma level 1 hospital in Youngstown, Ohio. The post-graduate residency program there is very intense, providing dental care with severe dental injuries and infections.

Dr. Wang performs all phases of general dentistry including oral surgery and root canal treatments. He is extremely competent in cosmetic restorative procedures like crowns, veneers, bridges and dentures. Dr. Wang is also a certified Invisalign provider with many years of experience.

Dr. Wang speaks fluent English, Mandarin, Cantonese and Taiwanese. His patients trust him to explain procedures thoroughly. His professionalism, patience, and gentle chairside manner makes him a favorite dental provider in our office. 


Dr. Adam Shing Ka Wu

Dr. Adam Shing Ka Wu grew up in Hong Kong and moved to America when he was 17. He graduated from UC Berkeley for his undergraduate studies in Economics, University of Arizona for his Master in Information Systems, and UCSF for his Doctor of Dental Surgery (DDS). While volunteering at a oncology clinic during his master studies, he saw the life-changing potential of health care and decided to pursue dentistry as a profession and means to serve his community around him. At UCSF, Dr. Wu was able to continue being involved in dental outreach to the community through health screenings and off-site clinics for the underserved. 

Dr. Wu has been practicing dentistry for over 10 years. He believes open communication is critical to a good relationship with his patients so he will patiently explain in understandable terms what the issues are, and how he intends to proactively re-establish health. Communication is always a two-way street, so he welcomes any and all questions.

In his free time, Dr. Wu likes to explore local eateries and spend as much time outside as the San Francisco sun allows. He enjoys traveling, snorkeling, swimming, rock climbing, windsurfing, hiking and many other outdoor activities.